Patient disposition, treatment characteristics and complications during induction. (A) Disposition of 647 newly diagnosed patients with APL treated with ATO-containing and non–ATO-containing regimens. Refer to the supplemental File 1 for details of treatment regimens used. (B) Trend in the distribution and number of patients treated with 4 different treatment regimens from 2001 to 2011. Refer to the supplemental File 1 for details of treatment regimens used. (C) Trends in the number and causes of early or induction deaths from 2001 to 2022. (D) Trends in the number of patients with APL-DS from 2001 to 2022. ICH, intracranial hemorrhage.