The effect of Affimer A11 on fibrin clot formation and lysis in plasma from different patient populations tested in turbidimetric assays. Clot lysis in healthy controls (A) and individual with T2DM (B) and CVD (C; n = 15 for each group). A 2-tailed, paired Student t test was performed for comparisons of the effect of Affimer A11 with scaffold-only Affimer control protein (SQT). T2DM, type 2 diabetes mellitus.