The CD3×CD3 BsAb treats mice with established xenogeneic GVHD. Mice were treated as in Figure 3. (A,C) Mice were frequently weighed, observed, and scored for GVHD. Area under the curve was compared between groups using ANOVA and multiple comparison analysis. (B) Survival analysis was done by log-rank test. n = 5 mice per group. Experiment was repeated 2 times.