Identification and management of patients at high-risk of cardiotoxicity. Clinical considerations for the screening and management of patients at an increased risk of cardiotoxicity undergoing T-cell–directed therapy. CKD, chronic kidney disease; CMR, cardiac magnetic resonance imaging; ECG, electrocardiography; ECOG, Eastern Cooperative Oncology Group; ESRD, end stage renal disease; GLS, global longitudinal strain; INR, international normalized ratio; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.