Patient clinical photographs and baseline laboratory studies. Photographs demonstrate a child with a capillary-venous- lymphatic malformation of the right lower extremity with overgrowth. Symptoms include pain, fatigue, and exercise intolerance. Laboratory studies were notable for an elevated D-dimer without any other hematologic abnormalities. Hgb, hemoglobin; PT, prothrombin time; PTT, partial prothrombin time; WBC, white blood cell count.