Structure of rilzabrutinib and proposed function in ITP. Mechanism of action of rilzabrutinib in ITP. Reproduced from Kuter et al. Rilzabrutinib versus placebo in adults and adolescents with persistent or chronic immune thrombocytopenia: LUNA 3 phase III study. Ther Adv Hematol. 2023;14. doi:10.1177/20406207231205431.