Presentation of all original continuous variables evaluated in cases and controls. Beeswarm panels of all original continuous variables evaluated in cases (N = 366) and the 3 control groups: hemoglobin, absolute neutrophil count, platelet count, triglycerides, fibrinogen, ferritin, sCD25, ALT, AST, LDH, bilirubin, albumin, and creatinine. These analyzed values presented do not include any imputed values. “Infection-1” includes 329 children with systemic infections that could be confused with MAS-HLH. “Infection-2” includes 361 children with severe sepsis treated at a pediatric ICU. “Rheuma” includes 374 children with systemic juvenile idiopathic arthritis, all without MAS-HLH.