Figure 4.
Comparison of deviation times from the recommendations of the EHRA guidelines and proposed remedial dosing regimens. (A) Deviation time from the recommendations of the EHRA guidelines and proposed remedial dosing regimens. (B) Difference in the deviation time between the recommendations of the EHRA guidelines and proposed remedial dosing regimens. The typical patient: age 60 years, body weight 70 kg, height 170 cm, serum creatinine 1 mg/dL, blood urea nitrogen 16 mg/dL, and without any potential comedication. Dosing regimens for each DOAC: rivaroxaban 20 mg q24h; edoxaban 60 mg q24h; apixaban 5 mg q12h; dabigatran 150 mg q12h. q12h, every 12 hours; q24h, every 24 hours.