Recommended remedial regimens when the DOAC dose was delayed for typical patient. The typical patient characteristics included the following: age 60 years, body weight 70 kg, height 170 cm, serum creatinine 1 mg/dL, blood urea nitrogen 16 mg/dL, and without any potential comedication. Strategy A, omit the missed dose and consume the next regular dose at the appointed time; strategy B, consume the regular dose immediately and omit the missed dose at the next appointed time; strategy C, consume the regular dose immediately and take a regular dose at the next appointed time; strategy D, consume the regular dose immediately and take a remedial dose at the next appointed time; strategy E, consume a remedial dose immediately and take a regular dose at the next appointed time; strategy F, consume the regular dose plus a remedial dose immediately and omit the next appointed dose; and strategy G, omit the missed dose and consume the regular dose plus a remedial dose at the next appointed time. DVT, deep vein thrombosis; PE, pulmonary embolism.