Structural models of the intrinsic tenase complex. (A-C) Schematic representation of FIXa-FVIIIa structural models assembled on a negatively charged lipid surface (anionic membrane) by Childers et al³³ (A), Venkateswarlu³² (B), and Madsen et al³⁴ (C). (D) Three-dimensional surface representation of the FIXa-FVIIIa structural model developed by Madsen et al.³⁴ The individual domains of FIXa (in yellow-orange) and FVIIIa (blue) are indicated. Figures were created with VMD 1.9.3. and BioRender.com.