Figure 2. FIXa serine protease domain.... | American Society of Hematology

Figure 2.

FIXa serine protease domain. Three-dimensional representations of the FIXa serine protease domain (Protein Data Bank ID 6MV4)22 with identification of the functional regions (A) and residues targeted for substitutions (B) that have been associated with enhanced FIX activity as a result of enhanced FVIIIa-dependent activity, FVIIIa-independent activity, or reduced inhibition. The figures were created with PyMol and BioRender.com.

FIXa serine protease domain. Three-dimensional representations of the FIXa serine protease domain (Protein Data Bank ID 6MV4)²² with identification of the functional regions (A) and residues targeted for substitutions (B) that have been associated with enhanced FIX activity as a result of enhanced FVIIIa-dependent activity, FVIIIa-independent activity, or reduced inhibition. The figures were created with PyMol and BioRender.com.

This Feature Is Available To Subscribers Only