Association between peak plasmin level and bleeding severity. Correlation between PG potential and bleeding severity reflected by the Vicenza and ISTH BAT bleeding scores, as well as the number of bleeding manifestations in patients with BDUC. The pathologic Vicenza bleeding score cutoff is ≥5 for women and ≥3 for men; the pathologic ISTH BAT bleeding score cutoff is ≥5 for women aged 18 to 30 years, >6 for women aged 31 to 51 years, ≥7 for women aged ≥52 years, and ≥4 for men. BS, bleeding score; ns, not significant.