Mutational landscape of LGLL. (A) Clinicomutational correlation. STAT3, STAT5B, and TET2 mutations have been associated with specific clinicobiological features. ∗Compared with wild-type STAT3. ∗∗CCL22 and STAT3 mutations are mutually exclusive. (B) Mutational landscape of LGLL (N = 120 patients). Courtesy of Cédric Pastoret, Hematology Department, Rennes University Hospital. AITL, angioimmunoblastic T-cell lymphoma; CMML, chronic myelomonocytic leukemia; MDS, myelodysplastic syndrome; Ref, references.