Association of HLA matching and donor age with clinical outcomes of allogeneic HCT from unrelated donors (UDs). Schematic representation of the risk associated with different combinations of donor age (young, ≤35 years; old, >35 years) and HLA-DP matching status by T-cell epitope in 10 of 10 HLA-matched UDs¹ or HLA class I matching status by PBM in 9 of 10 HLA-matched UDs.⁸ Lines and arrows indicate not significant difference compared with the reference (ref), or significantly (P < .05) higher (in red) or lower (in green) hazard ratio (HR) as depicted in the symbol legend. Matched, allele matched; NP, HLA-DP nonpermissive mismatched; P, HLA-DP permissive mismatched; PBM-m, HLA class I PBM matched; PBM-mm, HLA class I PBM mismatched. Figure created with BioRender.com.