Figure 2.
Combined MICA/B stabilization and memory-like NK cell transfer leads to early tumor control in vivo. (A) Experimental design. (B) Representative bioluminescence imaging (BLI) of recipient mice 9 and 12 days after engraftment with MM.1S-luc. Note the scale bar with lower intensities for the BLI signal in the 7C6-treated mice. (C) Enumeration of serial BLI measurements that show reduced tumor burden in mice receiving 7C6 mAb treatment compared with the isotype control. Differences were determined using the Mann-Whitney test; ns, P > .05; ∗P ≤ .05; ∗∗P ≤ .01; ∗∗∗P ≤ .001; ∗∗∗∗P ≤ .0001. IC, isotype control; ns, not significant.

Combined MICA/B stabilization and memory-like NK cell transfer leads to early tumor control in vivo. (A) Experimental design. (B) Representative bioluminescence imaging (BLI) of recipient mice 9 and 12 days after engraftment with MM.1S-luc. Note the scale bar with lower intensities for the BLI signal in the 7C6-treated mice. (C) Enumeration of serial BLI measurements that show reduced tumor burden in mice receiving 7C6 mAb treatment compared with the isotype control. Differences were determined using the Mann-Whitney test; ns, P > .05; ∗P ≤ .05; ∗∗P ≤ .01; ∗∗∗P ≤ .001; ∗∗∗∗P ≤ .0001. IC, isotype control; ns, not significant.

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