MAFs and P values for the CYP2C9 star variants across the 6 cohorts. The left and right panels respectively show the MAFs and negative log-transformed P values for the 7 CYP2C9 star variants. SNPs with MAFs of <1% were not analyzed in the respective cohorts. The cohorts are arranged by the proportion of African ancestry: War-PATH cohort 3 comprising 133 mixed ancestry South African participants (35.1% African ancestry); IWPC cohort comprising 316 African Americans recruited from USA (82.6% African ancestry); War-PATH cohort 4 comprising 94 mixed ancestry and Black Africans recruited from Uganda and South Africa (83.1% African ancestry); UAB cohort comprising 199 African Americans recruited from USA (83.7% African ancestry); War-PATH cohort 1 comprising 548 Black Africans from Uganda and South Africa (97.1% African ancestry); and, War-PATH cohort 2 comprising 214 Black Africans recruited from South Africa and Zimbabwe (98.6% African ancestry). CYP2C9, cytochrome P450, family 2, subfamily C, polypeptide 9.