Kaplan-Meier curves for OS and risk of AML evolution according to TP53 mutational status. (A) The median OS was 77.3 months (95% CI, 66.5-85.3) for TP53-wt; and 62.9 months (95% CI, 55.3-85.5) for TP53-mut patients (P = .25). (B) The risk of evolution to AML at 60 months was 19.7% for TP53-wt and 32.5% for TP53-mut patients (HR, 1.9; 95% CI, 1.3-2.8; P < .01). Ref., reference.