Role of pyridoxine (vitamin B6) in erythroid cells. (A) A schematic representation of the heme biosynthetic pathway in erythroid cells. (B) Effect of pyridoxine deprivation on the phenotype of XLSA and SLC25A38-CSA models. FECH, ferrochelatase; mf-PP, metal-free protoporphyrin IX; PD; pyridoxine deprivation; RBC, red blood cell.

Role of pyridoxine (vitamin B6) in erythroid cells. (A) A schematic representation of the heme biosynthetic pathway in erythroid cells. (B) Effect of pyridoxine deprivation on the phenotype of XLSA and SLC25A38-CSA models. FECH, ferrochelatase; mf-PP, metal-free protoporphyrin IX; PD; pyridoxine deprivation; RBC, red blood cell.

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