Quisinostat supports better engraftment of transduced cells in vivo. (A) Representative FACS plots of BM at 20 weeks after transplantation in primary mice. (B) Frequency of GFP⁺ cells in different organs (n = 5 mice per group; mean ± SEM; ∗∗P < .01). Statistical significance was calculated using 2-way ANOVA and multiple comparisons. (C) Frequency of transduced populations within huCD45⁺ in the BM at 20 weeks after transplantation in primary NSG mice (n = 5 mice per group; mean ± SEM; ∗P < .05, ∗∗P < .01). Statistical significance was calculated by 2-way ANOVA and multiple comparisons. (D) Schematic design of the secondary transplantation into NSG mice. (E) Human chimerism in the BM at 20 weeks after transplantation (n = 5 mice per group; mean ± SEM). Statistical significance was calculated using the Mann-Whitney test. (F) Frequency of transduced cells (GFP⁺) in the BM (n = 5 mice per group; mean ± SEM; ∗P < .05, ∗∗P < .01). Statistical significance was calculated using the Mann-Whitney test. CLP, common lymphoid progenitor.