Detection of hub genes in different cell populations. (A) Visualization of nodes (genes) in the AML appear network that have >2 connections. Node fill color indicates the cell population; node and label size indicate the node degree (number of correlations). Hub genes are annotated with their gene name. (B) Number of hub genes in LSCs, LPCs, CD8⁺, and CD4⁺ T cells for the appear network across AML risk groups. (C) Summary of significantly correlated hub genes in the different studied cell populations (LSCs, LPCs, CD8⁺, and CD4⁺ T cells).