Predictive value of clinical factors and platelet-related common genetic variants for platelet high responsiveness to ADP and epinephrine. Associations between platelet high aggregability induced by a low-response concentration (0.5 μM) of ADP and/or epi and clinical characteristics (A-B), platelet–related common genetic variants (C-D). The group comparisons, (A,C) ADP $±$ epi and (B,D) epi, were investigated using Poisson regressions with robust standard errors. The model was adjusted for age, sex, platelet count (C-D), plus platelet function-interfering medications (A-B). Alt, alternative allele; MI, myocardial infarction; Ref, reference allele.