Figure 4.
Risk of pneumonia and sepsis according to levels of plasma iron, transferrin saturation, and ferritin. Solid red lines are hazard ratios, broken black lines indicate 95% CIs. Analyses were multivariable adjusted for age, year of birth, sex, smoking status, cumulative smoking in pack-years, alcohol consumption, body mass index, menopausal status, study cohort, Charlson comorbidity index, and level of C-reactive protein. Reference for the continuous models (splines) is the median value of plasma iron (14 μmol/L), transferrin saturation (23%), or ferritin (100 μg/L) in the respective analyses. All individuals who had a measurement of iron, transferrin saturation, or ferritin were included in the categorical analyses and in modeling of the splines, but when drawing the spline curves, the x-axis was capped at the 99.9th percentile. ref., reference.

Risk of pneumonia and sepsis according to levels of plasma iron, transferrin saturation, and ferritin. Solid red lines are hazard ratios, broken black lines indicate 95% CIs. Analyses were multivariable adjusted for age, year of birth, sex, smoking status, cumulative smoking in pack-years, alcohol consumption, body mass index, menopausal status, study cohort, Charlson comorbidity index, and level of C-reactive protein. Reference for the continuous models (splines) is the median value of plasma iron (14 μmol/L), transferrin saturation (23%), or ferritin (100 μg/L) in the respective analyses. All individuals who had a measurement of iron, transferrin saturation, or ferritin were included in the categorical analyses and in modeling of the splines, but when drawing the spline curves, the x-axis was capped at the 99.9th percentile. ref., reference.

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