HRQoL deterioration by treatment arm. Results of the main analyses are indicated in green on the plot. Results of the two sensitivity analyses, 1 modifying the definition of deterioration by counting patients who discontinued the treatment as having a deterioration and 1 modifying the definition of deterioration by not counting patients who had a disease progression as having a deterioration are indicated in orange. CI, confidence interval; DEC, decitabine; N, number of patients with a deterioration; OR, odds ratio of a deterioration.