Effect of Rev-erbα on HIF2α translocation. (A) Immunoblot analysis of HIF2α in the nuclear extract in HepG2 cells. (B) Expression of HIF2α in HepG2 cells as measured by qRT-PCR. (C) Image analysis of HIF2α protein translocation by confocal microscopy as observed in HepG2 cells treated with DMOG or GSK4112 or combination for 24 hours. Data are representative and mean ± SD from 3 independent experiments.