Model-based figures of predicted PFS until 5 years after transplant with high-risk IPSS-R score at diagnosis. Figures are based on the multivariable Cox model for PFS including the interaction between prior treatment and change in IPSS-R score (Table 5). Figures are shown for no change in IPSS-R between diagnosis and transplant (A), improving IPSS-R score (B), and progressive IPSS-R score (C). Each of the curves refer to reference patients with high-risk IPSS-R score at diagnosis, aged 60 years, receiving a graft from a related donor after reduced intensity conditioning, and receiving a transplant 9 months after diagnosis. Chemo, chemotherapy; RIC, reduced intensity conditioning.