Number of VTE and major bleeding (high bleeding risk scenario). The impact analysis displaying the total number of VTE and major bleeding incurred for ASH panel recommendations R1 (A), R2 (B), R3 to R5 (C), and R6 (D) in the high–bleeding risk scenario. Five decision strategies are shown (from left to right): treat according to the threshold (Rx threshold; equation 3 in the manuscript); perform testing and act accordingly; test according to thresholds (equation 2 in the manuscript); treat none (give anticoagulants to no patient without testing); and treat all (provide anticoagulants for all patients without testing).