Reduced hemostatic activity in SVP model for f10^low mice. The number of clots over a 30-minute period observed for f10^WT mice (orange), f10^low mice (red), FVIII-deficient mice (f8^KO; gray), f10^low mice receiving purified FX (1 U/kg; blue or 5 U/kg; green). Each symbol represents an individual mouse. Horizontal bars represent median values. Statistical analysis was performed via 1-way ANOVA with Tukey correction for multiple comparisons.