Figure 1.
Number of T2 antigens recognized by EBVSTs from patients with lymphoma. Antigen specificity of EBVST lines generated from patient PBMCs enrolled in our clinical trial #NCT01555892. (A) Pie chart illustrating the number of T2 antigens recognized by 70 EBVST lines from 57 patients by stimulation of PBMCs with 4 EBV T2-pepmixes (EBNA-1, LMP-1, LMP-2, and BARF-1). A line was considered lacking specificity for an antigen if it produced <20 IFN-γ SFCs per 105 cells in response to the pepmix for that antigen, as measured in ELISpot assays.
