Immunoglobulin/TR rearrangements analysis. The figure shows the analysis of results obtained using the EuroClonality-NDC capture panel on genomic DNA from 52 patients in the BCP-LBL cohort. For each of the TR genes (TRA, TRB, TRD, and TRG) and immunoglobulin genes (IGH, IGK, and IGL), the number of clonal rearrangements identified is shown. Furthermore, information from the rearrangement sequence and segment usage were integrated to count the number of rearrangements defined as productive (complete rearrangements, potentially able to produce a functional receptor), unproductive (complete rearrangements unable to produce a receptor for the presence of out of frame deletions), and nonfunctional (incomplete, chimeric, or disruptive rearrangements).