Landscape of most recurrent genomic alterations in MF. (A) Landscape of genomic alterations in 67 tumor samples of MF divided into LR and HR disease based on the TNMB stages. Alterations are divided into SNVs and SCNAs. (B) Driver oncogene maps of JUNB and MAPK1. (C) Relative enrichment of signature activities per samples divided into LR, LR progressors, and HR.