Gene fusions of interest by ALL subtype. The most common subtypes across treatment arms were BCR::ABL1⁺, BCR::ABL1–like, low hypodiploidy, KMT2A rearranged, and DUX4 rearranged. The most common non–BCR::ABL1 rearrangements were IGH::CRLF2 detected in the BCR::ABL1–like subtype, and KMT2A::AFF1 detected in the KMT2A rearranged subtype. Oncoprint displays cases of both canonical and noncanonical fusion orientation. The numbers in parentheses denote the number of patients carrying that gene fusion.