Tet2 mRNA levels decrease in preleukemic self-renewing CD2-LMO2^tg thymocytes. (A) Percentage of CD45.2 in thymi of sublethal irradiated CD45.1 mice injected with bone marrow of WT mice (n = 4), thymus of WT mice (n = 4), thymus of CD2-Lmo2^tg/+ mice (n = 4) and thymus of Lck-Cre^tg/+Pten^fl/lf mice (n = 4). (B) Normalized Tet2 mRNA expression in the thymi of WT (n = 4) and CD2-Lmo2^tg/+ (n = 4) mice at 8 weeks (P = .0286) and 24 weeks (P = .0286) of age. (C) Normalized Tet2 mRNA expression in thymi of WT (n = 4) and Lck-Cre^tg/+Pten^fl/lf (n = 4) mice at 8 weeks of age (P = .2900).