Associations between selected genotypes and disease risk across 4 venous and arterial thrombosis phenotypes. A random-effects meta-analysis was used to generate effect size estimates for thrombosis risk across the 5 genotypes in 938 355 biorepository participants. For each comparison, noncarriers of both FVL and PTGM were used as the reference value (OR = 1.0). Closed circles represent the effect size estimates that are statistically significant after correction for multiple comparisons.