Timeline of antithrombotic therapy for discussed cases. For each case, the red circle represents the arterial thrombotic event, and the blue circle represents the venous thrombotic event. Time indicators reflect occurrence of events relative to the venous thrombotic event. Antithrombotic therapies are distinguished by colors, with red representing antiplatelet therapy, blue representing anticoagulation, and purple representing a combination of anticoagulation and antiplatelet therapy. ∗For all patients receiving therapeutic dose oral Xa inhibitors for venous thrombosis, an initiation dose is recommended (per package insert, and presented in Table 1). ASA, aspirin.