Waterfall plot for best change in marrow blast percentage. Shown are changes in absolute blast percentages in bone marrow aspirates at the time of best response compared with baseline. Note that 14 participants who did not have response assessment marrow biopsy because of circulating blasts are not included in this plot. Participants with no FLT3 mutation who had prior treatment with FLT3 inhibitors (purple bars with stars) had FLT3 mutations detected previously but not at the time of enrollment on this protocol.