Presence of microclots is an independent predictor of DIC and mortality in critically ill patients. (A) Multivariate analysis of crude and adjusted odds ratios (with patients adjusted for age and sex). The presence of microclots, as defined by microclot number (>1 per field) or size (>200 pixels per field), were independently associated with DIC development. (B) Multivariate analysis of crude and adjusted odds ratios (with patients adjusted for age and sex). The presence of microclots were independently associated with 28-day mortality.