OS of patients with VEXAS syndrome. (A) OS was not significantly different between those with or without thrombosis (P = .8). (B) Forest plot for survival. Using univariate Cox PH model, age at disease onset was significantly associated with survival (HR 1.07, P = .049) as were pulmonary manifestations or pulmonary effusions (HR 3.05, P < .0001). ∗P < .05. MSK, musculoskeletal; RP, relapsing polychondritis.