Quantifying the change in abundance of bacteria classified by source. (A) Percent of donor-only, recipient-only, and donor–recipient-shared species out of total bacterial abundance, based on donor and recipient microbiome profile at baseline. Lines are representative of individual participants, colored-coded according LGI response at day 28; CR (green), PR (blue), or NR (orange). (B) Top 5 influential species on beta diversity by nonparametric mean Bray-Curtis distance change within each sample at baseline and after FMT at day 7, day 14, and day 28. Bray-Curtis distance change was calculated by removing 1 species at a time and measuring the change in Bray-Curtis distance for each sample and adjusted with Shannon alphadiversity for that sample. Green dots show the species identified as donor exclusive, and blue dots show the shared species among donor and patients based on the first sample from donor and recipients. (C) Percent abundance of the top 5 species selected based on the nonparametric mean Bray-Curtis distance change at baseline and after FMT at day 7, day 14, and day 28.