Analysis of TE associations stratified based on PV risk group. (A) Subgroup analysis of high-risk PV identified HCT level >45%, WBC count >11 × 109/L, and PLT count >400 × 109/L as independently associated with TEs. (B) Only WBC count >11 × 109/L was identified to be associated with TE occurrence in patients with low-risk PV. The blue lines separating rows demark blood count data that were obtained from independent models. The significance of the association for sex, disease duration, and treatment with TE occurrence were unchanged and representative data for these covariates from the HCT level >45% model are shown (data for all models are shown in supplemental Figure 3). Significant values (P < .05) are indicated in blue font. Other treatments include ruxolitinib, anagrelide, interferon, busulfan, and chlorambucil.
