Time to restore ADAMTS13 activity after PEX end and days on PEX according to treatments. Patients were grouped according to treatments received. (A,C,E) Kaplan-Meier curves were constructed considering the time elapsed since the end of PEX therapy and the time required to achieve ADAMTS13 activity ≥20%, and the log-rank test was applied for comparisons between treatment schemes. Those patients whose ADAMTS13 levels were below 20% by the end of the study were censored at the date of the last test and are indicated in the curves. (B,D,F) The number of days from PEX end to ADAMTS13 recovery ≥20% were compared between treatment schemes. Those patients who did not recover ADAMTS13 activity by the end of the study were not considered. (G-I) The time patients were receiving PEX therapy was also compared between treatments. Capla, caplacizumab.