Eosinophil depletion by GATA1 deficiency reverses arterial thrombosis and reduces EETs and NETs in 10 weeks WTD-fed Lnk−/−Ldlr−/− recipient mice. (A) Eosinophil, neutrophil, and platelet counts in WT, △dblGATA, Lnk−/−, Lnk−/−△dblGATA BM recipient mice. (B) FeCl3-induced carotid artery occlusion in WT, △dblGATA, Lnk−/−, and Lnk−/−△dblGATA BM recipient mice. (C) Representative images of Fibrinogen (red) staining and EETs staining in carotid artery thrombi of WT, △dblGATA, Lnk−/−, and Lnk−/−△dblGATA BM recipient mice. EETs were quantified using MBP (green) with H3Cit (red). (D) Representative images and quantifications of NETs using MPO (green) with H3Cit (red) in thrombi of WT, △dblGATA, Lnk−/−, Lnk−/−△dblGATA BM recipient mice (n = 13 per group). (E) Quantification of eosinophil number (MBP+CD11b+) and neutrophil number (MPO+DAPI+) per thrombi. Scale bar, 100 μm. BM, bone marrow.