Association between baseline TMTV and tumor-infiltrated LAG3⁺ T cells with PFS and DOR. (A) Kaplan-Meier plots of PFS by TMTV. (B) Kaplan-Meier plots of DOR by TMTV. (C) Kaplan-Meier plots of PFS associated with percent LAG3⁺CD3⁺ cells in baseline tumors. (D) Kaplan-Meier plots of DOR associated with percent LAG3⁺CD3⁺ cells in baseline tumors. A cutoff (240 mL) at which most separation between PFS and DOR was derived and results are shown here. CD, cluster of differentiation; NE, not estimable.