CPX-351 promotes the abundance of eubiotic microbial modules. (A) PCoA of predicated functions and (B) SongBird differential analysis of relevant KEGG modules abundance with corresponding log-ratio rankings visualized with Qurro in mice treated IV as indicated. The CPX-351/“7 + 3” log-ratios of top 15 differential modules were selected to generate a box-whisker plot.¹⁸ (C) Table of KEGG Modules and (D) box and-whisker plots of relevant metabolic functions by PICRUSt2. ∗P < .05; ∗∗P < .01; CPX-351- vs “7 + 3”-treated mice, “7 + 3” vs none (untreated) mice. One-way ANOVA; Bonferroni multiple comparison test. Kruskal-Wallis test on all and pairwise samples.