Kaplan-Meier survival plots comparing WHO-HAEM5 defined patients. (A, B) OS and EFS between AML-MR and AML-DIFF. (C, D) OS and EFS between AML-MR without TP53 mutations (TP53⁻/MR⁺) and AML with mutated TP53 but without MR gene mutations (TP53⁺/MR⁻). (E, F) OS and EFS in AML-MR and AML-DIFF after excluding the TP53 mutations.