A way to “mimic” the pathophysiology of acquired SAA. In the companion article, Ben Hamza and colleagues provide data supporting a T cell–mediated, virus-induced etiology for the pathophysiology of acquired aplastic anemia. APC, antigen-presenting cell; HSC, hematopoietic stem cell; IFNγ, interferon gamma; IL-2, interleukin-2; MHC, major histocompatibility complex; TCR, T-cell receptor; TNFα, tumor necrosis factor α. Professional illustration by Patrick Lane, ScEYEnce Studios.