Fgl1 mRNA expression is induced in the mouse liver during anemia. Representative heat maps of the transcripts induced in the liver (A) and the bone marrow (B) at 24 and 48 hours compared to control mice at t = 0. Time course of Fgl1 mRNA expression in the liver (C) and the bone marrow (D) 1 to 6 days after phlebotomy in WT and Erfe^−/− mice (n = 5-8). WT and Erfe-/- as shown in Figure 1. Data shown are mean ± standard error of the mean (SEM) and were compared for each time point with values for control mice at t = 0 by 2-way ANOVA and were corrected for multiple comparisons by the Holm-Šidák method (C-D). ∗∗∗∗P < .0001; ∗∗∗P < .001; ∗P < .05.