Expression of DC-SIGN in FL tissue. A representative case of FL is shown without (left) or with (right) staining with antiDC-SIGN by immunofluorescence. In the left panel, M2 macrophages, mainly in the interfollicular area, are stained red with anti-CD163, and FDCs in the neoplastic follicles outlined in dotted white lines are stained blue with anti-CD23. In the right panel, M2 macrophages costained with green anti-DC-SIGN appear yellow. FDCs costained with green anti-DC-SIGN appear cyan.