Among 5353 patients alive at 1 year after HCT, those who survived ICU in the first year had worse 5-year survival than those who never required ICU. (A) Landmark analysis of only patients surviving to HCT day +365. Kaplan-Meier estimates of OS from transplant day +365 for all patients (top left), those with malignant disease (top middle), and those with nonmalignant disease (bottom left), stratified by need for intensive care in the first year after HCT. Cumulative incidence of TRM (bottom middle) among patients who underwent transplantation for malignancy is also shown. (B) Among those alive at HCT day +365, factors independently associated with long-term survival from transplant day +365 to last follow-up in multivariable Cox regression.