Figure 1.
Key MCL-related clinical, pathologic, and genomic characteristics in evaluable patients. Each column represents an individual patient. Relevant genes with abnormalities detected in at least 1 patient (≥5% prevalence) are shown. Colored squares indicate the presence of a genomic abnormality or clinical feature and individual colors the nature of the change. Deletions were detected by a combination of fluorescent in-situ hybridization, or where not available by next-generation sequencing-based copy number analysis. Multihit is defined as the presence of >1 mutations occurring in the same gene in the same sample. Two patients did not have next-generation sequencing data available (patients 12 and 14).