Three candidate KIR genotypes are associated with altered relapse incidence in the CIBMTR cohort but not the DRST cohort. (A) Heat map of the KIRs included in each of the candidate genotypes, with haplotype AA as a reference. Of these, 3 were selected through a screening for association with relapse compared with patients receiving AA grafts. (B) G5 in all patients and (C) G3 in patients with HLA-Bw4/Bx were associated with significant decrease in relapse incidence, and (D) G2 was associated with increased relapse incidence among patients homozygous for HLA-C1; however, these results could not be replicated in an independent external cohort.